Synthesis of methylenebis(phosphonate) analogues of nucleotide coenzymes. A novel coupling mechanism

Krzysztof W Pankiewicz; Krystyna B. Lesiak; Kyoichi A. Watanabe

doi:10.1080/10426509908546334

Synthesis of methylenebis(phosphonate) analogues of nucleotide coenzymes. A novel coupling mechanism

Krzysztof W Pankiewicz, Krystyna B. Lesiak, Kyoichi A. Watanabe

Center for Drug Design

Research output: Contribution to journal › Article › peer-review

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Abstract

Synthesis of P¹, P²-disubstituted methylenebis(phosphonate)s as inhibitors of inosine monophosphate dehydrogenase is presented.

Original language	English (US)
Pages (from-to)	671-674
Number of pages	4
Journal	Phosphorus, Sulfur and Silicon and Related Elements
Volume	144-146
DOIs	https://doi.org/10.1080/10426509908546334
State	Published - Jan 1 1999

Keywords

Inhibitors of IMPDH
Methylenebis(phosphonate)s

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10.1080/10426509908546334

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title = "Synthesis of methylenebis(phosphonate) analogues of nucleotide coenzymes. A novel coupling mechanism",

abstract = "Synthesis of P1, P2-disubstituted methylenebis(phosphonate)s as inhibitors of inosine monophosphate dehydrogenase is presented.",

keywords = "Inhibitors of IMPDH, Methylenebis(phosphonate)s",

author = "Pankiewicz, {Krzysztof W} and Lesiak, {Krystyna B.} and Watanabe, {Kyoichi A.}",

year = "1999",

month = jan,

day = "1",

doi = "10.1080/10426509908546334",

language = "English (US)",

volume = "144-146",

pages = "671--674",

journal = "Phosphorus, Sulfur and Silicon and the Related Elements",

issn = "1042-6507",

publisher = "Taylor and Francis Ltd.",

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T1 - Synthesis of methylenebis(phosphonate) analogues of nucleotide coenzymes. A novel coupling mechanism

AU - Pankiewicz, Krzysztof W

AU - Lesiak, Krystyna B.

AU - Watanabe, Kyoichi A.

PY - 1999/1/1

Y1 - 1999/1/1

N2 - Synthesis of P1, P2-disubstituted methylenebis(phosphonate)s as inhibitors of inosine monophosphate dehydrogenase is presented.

AB - Synthesis of P1, P2-disubstituted methylenebis(phosphonate)s as inhibitors of inosine monophosphate dehydrogenase is presented.

KW - Inhibitors of IMPDH

KW - Methylenebis(phosphonate)s

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U2 - 10.1080/10426509908546334

DO - 10.1080/10426509908546334

M3 - Article

AN - SCOPUS:4243740690

VL - 144-146

SP - 671

EP - 674

JO - Phosphorus, Sulfur and Silicon and the Related Elements

JF - Phosphorus, Sulfur and Silicon and the Related Elements

SN - 1042-6507

ER -

Synthesis of methylenebis(phosphonate) analogues of nucleotide coenzymes. A novel coupling mechanism

Abstract

Keywords

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