Synthesis of fluoro and trifluoromethyl derivatives of 2‐phenylquinolin‐4‐ol

Lubomir Janda, Johnny Nguyen, Steven E. Patterson, Lucjan Strekowski

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


A tert‐butoxide base‐mediated cyclization of fluoro‐ and trifluoromethyl‐substituted Schiff bases 12‐19 produces 4‐tert‐butoxyquinolines 23‐30 which are hydrolyzed to quinolin‐4‐ols 31‐38.

Original languageEnglish (US)
Pages (from-to)1753-1756
Number of pages4
JournalJournal of Heterocyclic Chemistry
Issue number7
StatePublished - Dec 1992

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