Synthesis of fluoro and trifluoromethyl derivatives of 2‐phenylquinolin‐4‐ol

Lubomir Janda; Johnny Nguyen; Steven E. Patterson; Lucjan Strekowski

doi:10.1002/jhet.5570290713

Synthesis of fluoro and trifluoromethyl derivatives of 2‐phenylquinolin‐4‐ol

Lubomir Janda, Johnny Nguyen, Steven E. Patterson, Lucjan Strekowski

Center for Drug Design

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

A tert‐butoxide base‐mediated cyclization of fluoro‐ and trifluoromethyl‐substituted Schiff bases 12‐19 produces 4‐tert‐butoxyquinolines 23‐30 which are hydrolyzed to quinolin‐4‐ols 31‐38.

Original language	English (US)
Pages (from-to)	1753-1756
Number of pages	4
Journal	Journal of Heterocyclic Chemistry
Volume	29
Issue number	7
DOIs	https://doi.org/10.1002/jhet.5570290713
State	Published - Dec 1992

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10.1002/jhet.5570290713

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@article{db2c2857b8c543c98fa5b711dffccb04,

title = "Synthesis of fluoro and trifluoromethyl derivatives of 2‐phenylquinolin‐4‐ol",

abstract = "A tert‐butoxide base‐mediated cyclization of fluoro‐ and trifluoromethyl‐substituted Schiff bases 12‐19 produces 4‐tert‐butoxyquinolines 23‐30 which are hydrolyzed to quinolin‐4‐ols 31‐38.",

author = "Lubomir Janda and Johnny Nguyen and Patterson, {Steven E.} and Lucjan Strekowski",

year = "1992",

month = dec,

doi = "10.1002/jhet.5570290713",

language = "English (US)",

volume = "29",

pages = "1753--1756",

journal = "Journal of Heterocyclic Chemistry",

issn = "0022-152X",

publisher = "John Wiley and Sons Inc.",

number = "7",

}

TY - JOUR

T1 - Synthesis of fluoro and trifluoromethyl derivatives of 2‐phenylquinolin‐4‐ol

AU - Janda, Lubomir

AU - Nguyen, Johnny

AU - Patterson, Steven E.

AU - Strekowski, Lucjan

PY - 1992/12

Y1 - 1992/12

N2 - A tert‐butoxide base‐mediated cyclization of fluoro‐ and trifluoromethyl‐substituted Schiff bases 12‐19 produces 4‐tert‐butoxyquinolines 23‐30 which are hydrolyzed to quinolin‐4‐ols 31‐38.

AB - A tert‐butoxide base‐mediated cyclization of fluoro‐ and trifluoromethyl‐substituted Schiff bases 12‐19 produces 4‐tert‐butoxyquinolines 23‐30 which are hydrolyzed to quinolin‐4‐ols 31‐38.

UR - http://www.scopus.com/inward/record.url?scp=84986513636&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84986513636&partnerID=8YFLogxK

U2 - 10.1002/jhet.5570290713

DO - 10.1002/jhet.5570290713

M3 - Article

AN - SCOPUS:84986513636

SN - 0022-152X

VL - 29

SP - 1753

EP - 1756

JO - Journal of Heterocyclic Chemistry

JF - Journal of Heterocyclic Chemistry

IS - 7

ER -

Synthesis of fluoro and trifluoromethyl derivatives of 2‐phenylquinolin‐4‐ol

Abstract

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