Synthesis of cyclic peptide hybrids with amino acid and nucleobase side- chains

Marta Planas; Eduard Bardají; George Barany

doi:10.1016/S0040-4039(00)00550-5

Synthesis of cyclic peptide hybrids with amino acid and nucleobase side- chains

Marta Planas, Eduard Bardají, George Barany

Chemistry (Twin Cities)

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Head-to-tail cyclic peptides with hybrid side-chains have been synthesized by solid-phase assembly of the linear sequences, followed by PyAOP/HOAt/DIEA-mediated cyclization either while resin-bound or, after cleavage, in solution. (C) 2000 Elsevier Science Ltd.

Original language	English (US)
Pages (from-to)	4097-4100
Number of pages	4
Journal	Tetrahedron Letters
Volume	41
Issue number	21
DOIs	https://doi.org/10.1016/S0040-4039(00)00550-5
State	Published - May 29 2000

Bibliographical note

Funding Information:
M.P. is grateful to the Ministerio de Educación y Cultura (Spain) for a postdoctoral fellowship, E.B. acknowledges grant Nos. QFN-4620 and UdG98/404, and G.B. thanks NIH for grant No. 42722. We are also grateful to Professor C. Cativiela for providing H-Acc-OH.

Keywords

Cyclization
Peptide nucleic acids
Solid-phase synthesis

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10.1016/S0040-4039(00)00550-5

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title = "Synthesis of cyclic peptide hybrids with amino acid and nucleobase side- chains",

abstract = "Head-to-tail cyclic peptides with hybrid side-chains have been synthesized by solid-phase assembly of the linear sequences, followed by PyAOP/HOAt/DIEA-mediated cyclization either while resin-bound or, after cleavage, in solution. (C) 2000 Elsevier Science Ltd.",

keywords = "Cyclization, Peptide nucleic acids, Solid-phase synthesis",

author = "Marta Planas and Eduard Bardaj{\'i} and George Barany",

note = "Funding Information: M.P. is grateful to the Ministerio de Educaci{\'o}n y Cultura (Spain) for a postdoctoral fellowship, E.B. acknowledges grant Nos. QFN-4620 and UdG98/404, and G.B. thanks NIH for grant No. 42722. We are also grateful to Professor C. Cativiela for providing H-Acc-OH.",

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doi = "10.1016/S0040-4039(00)00550-5",

language = "English (US)",

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T1 - Synthesis of cyclic peptide hybrids with amino acid and nucleobase side- chains

AU - Planas, Marta

AU - Bardají, Eduard

AU - Barany, George

N1 - Funding Information: M.P. is grateful to the Ministerio de Educación y Cultura (Spain) for a postdoctoral fellowship, E.B. acknowledges grant Nos. QFN-4620 and UdG98/404, and G.B. thanks NIH for grant No. 42722. We are also grateful to Professor C. Cativiela for providing H-Acc-OH.

PY - 2000/5/29

Y1 - 2000/5/29

N2 - Head-to-tail cyclic peptides with hybrid side-chains have been synthesized by solid-phase assembly of the linear sequences, followed by PyAOP/HOAt/DIEA-mediated cyclization either while resin-bound or, after cleavage, in solution. (C) 2000 Elsevier Science Ltd.

AB - Head-to-tail cyclic peptides with hybrid side-chains have been synthesized by solid-phase assembly of the linear sequences, followed by PyAOP/HOAt/DIEA-mediated cyclization either while resin-bound or, after cleavage, in solution. (C) 2000 Elsevier Science Ltd.

KW - Cyclization

KW - Peptide nucleic acids

KW - Solid-phase synthesis

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U2 - 10.1016/S0040-4039(00)00550-5

DO - 10.1016/S0040-4039(00)00550-5

M3 - Article

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VL - 41

SP - 4097

EP - 4100

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 21

ER -

Synthesis of cyclic peptide hybrids with amino acid and nucleobase side- chains

Abstract

Bibliographical note

Keywords

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