Synthesis of an Acylphosphate Driven by a Proton Gradient. A Model for H+-ATPase

Ian J. Colton; Romas J. Kazlauskas

doi:10.1021/jo00052a003

Synthesis of an Acylphosphate Driven by a Proton Gradient. A Model for H⁺-ATPase

Ian J. Colton
, Romas J. Kazlauskas

Biotechnology Institute

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

We describe the first model for a proton pump, H⁺-ATPase. This model uses the energy from an indirect transfer of two protons from a solution at pH 0.3 to a solution at pH 10 to drive the synthesis of a high-energy phosphate, citraconyl phosphate.

Original language	English (US)
Pages (from-to)	7005-7006
Number of pages	2
Journal	Journal of Organic Chemistry
Volume	57
Issue number	26
DOIs	https://doi.org/10.1021/jo00052a003
State	Published - Dec 1 1992

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title = "Synthesis of an Acylphosphate Driven by a Proton Gradient. A Model for H+-ATPase",

abstract = "We describe the first model for a proton pump, H+-ATPase. This model uses the energy from an indirect transfer of two protons from a solution at pH 0.3 to a solution at pH 10 to drive the synthesis of a high-energy phosphate, citraconyl phosphate.",

author = "Colton, \{Ian J.\} and Kazlauskas, \{Romas J.\}",

year = "1992",

month = dec,

day = "1",

doi = "10.1021/jo00052a003",

language = "English (US)",

volume = "57",

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journal = "Journal of Organic Chemistry",

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AU - Kazlauskas, Romas J.

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N2 - We describe the first model for a proton pump, H+-ATPase. This model uses the energy from an indirect transfer of two protons from a solution at pH 0.3 to a solution at pH 10 to drive the synthesis of a high-energy phosphate, citraconyl phosphate.

AB - We describe the first model for a proton pump, H+-ATPase. This model uses the energy from an indirect transfer of two protons from a solution at pH 0.3 to a solution at pH 10 to drive the synthesis of a high-energy phosphate, citraconyl phosphate.

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UR - https://www.scopus.com/pages/publications/33751391659#tab=citedBy

U2 - 10.1021/jo00052a003

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M3 - Article

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JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

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ER -

Synthesis of an Acylphosphate Driven by a Proton Gradient. A Model for H⁺-ATPase

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