Synthesis of an Acylphosphate Driven by a Proton Gradient. A Model for H+-ATPase

Ian J. Colton; Romas J. Kazlauskas

doi:10.1021/jo00052a003

Synthesis of an Acylphosphate Driven by a Proton Gradient. A Model for H⁺-ATPase

Ian J. Colton, Romas J. Kazlauskas

Biotechnology Institute

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

We describe the first model for a proton pump, H⁺-ATPase. This model uses the energy from an indirect transfer of two protons from a solution at pH 0.3 to a solution at pH 10 to drive the synthesis of a high-energy phosphate, citraconyl phosphate.

Original language	English (US)
Pages (from-to)	7005-7006
Number of pages	2
Journal	Journal of Organic Chemistry
Volume	57
Issue number	26
DOIs	https://doi.org/10.1021/jo00052a003
State	Published - Dec 1 1992

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title = "Synthesis of an Acylphosphate Driven by a Proton Gradient. A Model for H+-ATPase",

abstract = "We describe the first model for a proton pump, H+-ATPase. This model uses the energy from an indirect transfer of two protons from a solution at pH 0.3 to a solution at pH 10 to drive the synthesis of a high-energy phosphate, citraconyl phosphate.",

author = "Colton, {Ian J.} and Kazlauskas, {Romas J.}",

year = "1992",

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Synthesis of an Acylphosphate Driven by a Proton Gradient. A Model for H⁺-ATPase

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