TY - JOUR
T1 - Synthesis of 5-substituted 4,5,6,7-tetrahydroindoles from cyclohexanones
AU - Lee, Chang Kiu
AU - Lee, In Sook Han
AU - Noland, Wayland E.
PY - 2007/2/1
Y1 - 2007/2/1
N2 - 5-Substituted 4,5,6,7-tetrahydroindoles were prepared from 4-substituted cyclohexanones in three steps: conversion to an enol silyl ether, introduction of a formylmethyl group at 2-C, and the Paal-Knorr pyrrole synthesis by reacting the 1,4-dicarbonyl compounds with ammonia. The substituents are H, methyl, ethyl, tert-butyl, methoxy, and phenyl.
AB - 5-Substituted 4,5,6,7-tetrahydroindoles were prepared from 4-substituted cyclohexanones in three steps: conversion to an enol silyl ether, introduction of a formylmethyl group at 2-C, and the Paal-Knorr pyrrole synthesis by reacting the 1,4-dicarbonyl compounds with ammonia. The substituents are H, methyl, ethyl, tert-butyl, methoxy, and phenyl.
UR - http://www.scopus.com/inward/record.url?scp=34548810751&partnerID=8YFLogxK
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U2 - 10.3987/com-06-10933
DO - 10.3987/com-06-10933
M3 - Article
AN - SCOPUS:34548810751
VL - 71
SP - 419
EP - 428
JO - Heterocycles
JF - Heterocycles
SN - 0385-5414
IS - 2
ER -