Synthesis of 1,2,4-thiadiazoles by oxidative dimerization of carbothioamides by using oxone

Akira Yoshimura; Anthony D. Todora; Brent J. Kastern; Steven R. Koski; Viktor Zhdankin

doi:10.1002/ejoc.201402756

Synthesis of 1,2,4-thiadiazoles by oxidative dimerization of carbothioamides by using oxone

Akira Yoshimura, Anthony D. Todora, Brent J. Kastern, Steven R. Koski, Viktor Zhdankin

Chemistry & Biochemistry

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

1,2,4-Thiadiazoles were efficiently synthesized in good yields through the oxidative dimerization of carbothioamides by using Oxone as a readily available, inexpensive, and environmentally safe oxidant. A similar reaction of phenylselenoamide led to the corresponding 1,2,4-phenylselenadiazole in high yield.

Original language	English (US)
Pages (from-to)	5149-5152
Number of pages	4
Journal	European Journal of Organic Chemistry
Volume	2014
Issue number	24
DOIs	https://doi.org/10.1002/ejoc.201402756
State	Published - Aug 2014

Keywords

Heterocycles
Oxidation
Oxone
Selenium
Sulfur

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10.1002/ejoc.201402756

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title = "Synthesis of 1,2,4-thiadiazoles by oxidative dimerization of carbothioamides by using oxone",

abstract = "1,2,4-Thiadiazoles were efficiently synthesized in good yields through the oxidative dimerization of carbothioamides by using Oxone as a readily available, inexpensive, and environmentally safe oxidant. A similar reaction of phenylselenoamide led to the corresponding 1,2,4-phenylselenadiazole in high yield.",

keywords = "Heterocycles, Oxidation, Oxone, Selenium, Sulfur",

author = "Akira Yoshimura and Todora, {Anthony D.} and Kastern, {Brent J.} and Koski, {Steven R.} and Viktor Zhdankin",

year = "2014",

month = aug,

doi = "10.1002/ejoc.201402756",

language = "English (US)",

volume = "2014",

pages = "5149--5152",

journal = "Justus Liebigs Annalen der Chemie",

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T1 - Synthesis of 1,2,4-thiadiazoles by oxidative dimerization of carbothioamides by using oxone

AU - Yoshimura, Akira

AU - Todora, Anthony D.

AU - Kastern, Brent J.

AU - Koski, Steven R.

AU - Zhdankin, Viktor

PY - 2014/8

Y1 - 2014/8

N2 - 1,2,4-Thiadiazoles were efficiently synthesized in good yields through the oxidative dimerization of carbothioamides by using Oxone as a readily available, inexpensive, and environmentally safe oxidant. A similar reaction of phenylselenoamide led to the corresponding 1,2,4-phenylselenadiazole in high yield.

AB - 1,2,4-Thiadiazoles were efficiently synthesized in good yields through the oxidative dimerization of carbothioamides by using Oxone as a readily available, inexpensive, and environmentally safe oxidant. A similar reaction of phenylselenoamide led to the corresponding 1,2,4-phenylselenadiazole in high yield.

KW - Heterocycles

KW - Oxidation

KW - Oxone

KW - Selenium

KW - Sulfur

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U2 - 10.1002/ejoc.201402756

DO - 10.1002/ejoc.201402756

M3 - Article

AN - SCOPUS:84906057516

SN - 1434-193X

VL - 2014

SP - 5149

EP - 5152

JO - Justus Liebigs Annalen der Chemie

JF - Justus Liebigs Annalen der Chemie

IS - 24

ER -

Synthesis of 1,2,4-thiadiazoles by oxidative dimerization of carbothioamides by using oxone

Abstract

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