Synthesis, microbiological study and X-ray structural characterisation of a tri-n-butylstannyl-2[4(diethylamino)arylazo]benzenecarboxylate

Sibani Chakraborty, Asim K. Bera, Suparna Bhattacharya, Sreya Ghosh, Asok K. Pal, Soumen Ghosh, Asok Banerjee

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Organostannyl carboxylates adopt an interesting range of structural variations leading to different structure-activity relationship. Organostanny1-2(arylazo)benzenecarboxylates, reported here, inhibit Gram-positive bacterial growth with an average MIC 10-20 μg ml-1, which is below the lethal dose. The discrete molecular units of this series of compounds function as an anisobidentate chelating ligand, thus rendering the Sn atom five coordinated and adopt a polymeric form. The present work reports the X-ray crystallographic structure of tri-n-butylstannyl-2[4(diethylamino)arylazo]benzenecarboxylate and microbial studies in order to get insight into the mode of action of such compounds in biology.

Original languageEnglish (US)
Pages (from-to)33-38
Number of pages6
JournalJournal of Organometalic Chemistry
Volume645
Issue number1-2
DOIs
StatePublished - Feb 18 2002

Keywords

  • Crystal structures
  • Structure-activity
  • Tributyltin analogs
  • Triorgano stannyl

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