Synthesis, antiinflammatory and antibacterial activities of 4-substituted phenyl benzimidazoles

J. T. Leonard, L. Jeyaseeli, O. S. Rajesh, K. Murugesh, R. Sivakumar, V. Gunasekaran

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

A new series of substituted benzimidazoles as 1-(substituted methyl)-2-(substituted phenyl) benzimidazoles were synthesized and characterized by IR, 1H NMR and elemental analysis. The compounds were evaluated for antiinflammatory and antibacterial activities. All the compounds exhibited significant to moderate antiinflammatory and antibacterial activities.

Original languageEnglish (US)
Pages (from-to)1104-1108
Number of pages5
JournalAsian Journal of Chemistry
Volume18
Issue number2
StatePublished - 2006
Externally publishedYes

Keywords

  • 2-Phenyl benzimidazole
  • Antibacterial
  • Antiinflammatory
  • Mannich bases

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