Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives

José Trujillo-Ferrara; Leticia Montoya Cano; Michel Espinoza-Fonseca

doi:10.1016/S0960-894X(03)00198-7

Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives

José Trujillo-Ferrara
, Leticia Montoya Cano
, Michel Espinoza-Fonseca

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

The synthesis, acetylcholinesterase inhibitory capacity and structure-activity relationships of simple-structured m-Aminobenzoic acid derivatives are reported. Compound 1b was found to be more potent than galanthamine and tacrine in inhibiting acetylcholinesterase.

Original language	English (US)
Pages (from-to)	1825-1827
Number of pages	3
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	13
Issue number	10
DOIs	https://doi.org/10.1016/S0960-894X(03)00198-7
State	Published - May 19 2003
Externally published	Yes

Bibliographical note

Funding Information:
The authors would like to thank Dr. Hiram I. Beltrán for the suggestions made to the discussion and CONACYT and SEGEPI-IPN for financial support.

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10.1016/S0960-894X(03)00198-7

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title = "Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives",

abstract = "The synthesis, acetylcholinesterase inhibitory capacity and structure-activity relationships of simple-structured m-Aminobenzoic acid derivatives are reported. Compound 1b was found to be more potent than galanthamine and tacrine in inhibiting acetylcholinesterase.",

author = "Jos{\'e} Trujillo-Ferrara and \{Montoya Cano\}, Leticia and Michel Espinoza-Fonseca",

note = "Funding Information: The authors would like to thank Dr. Hiram I. Beltr{\'a}n for the suggestions made to the discussion and CONACYT and SEGEPI-IPN for financial support.",

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T1 - Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives

AU - Trujillo-Ferrara, José

AU - Montoya Cano, Leticia

AU - Espinoza-Fonseca, Michel

N1 - Funding Information: The authors would like to thank Dr. Hiram I. Beltrán for the suggestions made to the discussion and CONACYT and SEGEPI-IPN for financial support.

PY - 2003/5/19

Y1 - 2003/5/19

N2 - The synthesis, acetylcholinesterase inhibitory capacity and structure-activity relationships of simple-structured m-Aminobenzoic acid derivatives are reported. Compound 1b was found to be more potent than galanthamine and tacrine in inhibiting acetylcholinesterase.

AB - The synthesis, acetylcholinesterase inhibitory capacity and structure-activity relationships of simple-structured m-Aminobenzoic acid derivatives are reported. Compound 1b was found to be more potent than galanthamine and tacrine in inhibiting acetylcholinesterase.

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UR - https://www.scopus.com/pages/publications/0038743108#tab=citedBy

U2 - 10.1016/S0960-894X(03)00198-7

DO - 10.1016/S0960-894X(03)00198-7

M3 - Article

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AN - SCOPUS:0038743108

SN - 0960-894X

VL - 13

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JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 10

ER -

Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives

Abstract

Bibliographical note

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