Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives

José Trujillo-Ferrara, Leticia Montoya Cano, Michel Espinoza-Fonseca

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

The synthesis, acetylcholinesterase inhibitory capacity and structure-activity relationships of simple-structured m-Aminobenzoic acid derivatives are reported. Compound 1b was found to be more potent than galanthamine and tacrine in inhibiting acetylcholinesterase.

Original languageEnglish (US)
Pages (from-to)1825-1827
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume13
Issue number10
DOIs
StatePublished - May 19 2003

Bibliographical note

Funding Information:
The authors would like to thank Dr. Hiram I. Beltrán for the suggestions made to the discussion and CONACYT and SEGEPI-IPN for financial support.

Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.

Fingerprint

Dive into the research topics of 'Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives'. Together they form a unique fingerprint.

Cite this