Synthesis and X-ray crystal structure of 1-cyano-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ 3,2-benzoiodoxole, a stable cyanoiodolane

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Abstract

Stable, crystalline cyanoiodolane 3 has been prepared in two steps by sequential reactions of 1-hydroxy-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ 3,2-benzoiodoxole 1 with trimethylsilyltriflate and then with cyanotrimethysilane; X-ray structure analysis reveals a distorted T-shaped structure for iodine with an endocyclic I-O bond distance of 2.117 Å, which is significantly shorter than usual in C-substituted benzoiodoxole derivatives.

Original languageEnglish (US)
Pages (from-to)50-51
Number of pages2
JournalMendeleev Communications
Volume6
Issue number2
DOIs
StatePublished - 1996

Bibliographical note

Funding Information:
This work was supported by the National Science Foundation [NSF/CHE-9505868] at UMD and by the NCI of NIH [2ROCA16903] at Utah.

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