Synthesis and evaluation of acridine- and acridone-based anti-herpes agents with topoisomerase activity

Keyphrases

• Acridine 100%
• Acridone 100%
• Antiherpes 100%
• Topoisomerase Activity 100%
• Mechanism of Action 60%
• Herpesvirus Infection 60%
• Topoisomerase II 40%
• Amsacrine 40%
• Virus 20%
• Anticancer Agents 20%
• Amino 20%
• Herpes Simplex 20%
• Resistant Strains 20%
• Topoisomerase 20%
• DNA Topoisomerase 20%
• Compound Function 20%
• Whole Cell 20%
• Nucleosides 20%
• Supercoiled DNA 20%
• Carboxamide 20%
• Triaryl 20%
• Antiviral Compounds 20%
• Cleavage Assay 20%
• Heterocyclic Compounds 20%
• Aclarubicin 20%
• Amino Functionality 20%
• Herpes Simplex Type 2 20%
• Xanthones 20%
• Unnatural nucleotides 20%
• Unique Mechanism 20%

Pharmacology, Toxicology and Pharmaceutical Science

• DNA Topoisomerase (ATP Hydrolysing) 100%
• DNA Topoisomerase 100%
• Acridone Derivative 100%
• Herpes Simplex 100%
• Acridine 100%
• Amsacrine 66%
• Herpes Virus Infection 66%
• Acridine Derivative 66%
• Nucleoside 66%
• Heterocyclic Compound 33%
• Antiviral Drug 33%
• Xanthone Derivative 33%
• Carboxamide 33%
• Aclarubicin 33%
• Anticancer Drug 33%