Synthesis and characterization of melting copoly(lactic-glycolic acid)

Yanling Cheng, M. A. Liu-Qiang, Feng Shu-Hua, L. I. Ruo-Hui, Shaobo Deng

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Lactic-glycolic acid polymer composite (PLGA) combined their respective advantages of poly(lactic acid) and poly(glycolic acid), meanwhile developed some new functions such as better controlled biodegradation, mechanic features, physics and chemistry and so on. Poly (lactic-glycolic Acid) were synthesized directly by melting polymerization with lactic acid and glycolic acid as monomers. The paper shows the influence factors on copolymer intrinsic viscosity including polymerization time, catalyst category, mixing speed, monomer ratio. The optimum reaction conditions are: the ratio of LA/GA 1:1, reaction time 10 hours, catalyst stannous chloride, stirred speed 200r/min. The structure, appearance and biodegradation of copolymer are characterized.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Polymer Composites
Subtitle of host publicationProperties,Performance and Applications
PublisherNova Science Publishers, Inc.
Pages1173-1179
Number of pages7
ISBN (Print)9781607417170
StatePublished - Jan 1 2011

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