Synthesis and biological evaluation of novel benzoxaboroles as potential antimicrobial and anticancer agents

J. Sravan Kumar; M. A. Alam; Shirisha Gurrapu; Grady Nelson; Michael Williams; Michael A. Corsello; Joseph L. Johnson; Subash C. Jonnalagadda; Venkatram R. Mereddy

doi:10.1002/jhet.1777

Synthesis and biological evaluation of novel benzoxaboroles as potential antimicrobial and anticancer agents

J. Sravan Kumar, M. A. Alam, Shirisha Gurrapu, Grady Nelson, Michael Williams, Michael A. Corsello, Joseph L. Johnson, Subash C. Jonnalagadda, Venkatram R. Mereddy

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22 Scopus citations

Abstract

Several novel benzoxaborole derivatives were synthesized starting from 2-formylphenylboronic acid utilizing Baylis-Hillman reaction, Barbier allylation, Passerini reaction, and aldol reaction protocols as the key step. All the synthesized benzoxaboroles have been evaluated for their antibacterial, antifungal, and anticancer activities.

Original language	English (US)
Pages (from-to)	814-820
Number of pages	7
Journal	Journal of Heterocyclic Chemistry
Volume	50
Issue number	4
DOIs	https://doi.org/10.1002/jhet.1777
State	Published - Jul 2013

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title = "Synthesis and biological evaluation of novel benzoxaboroles as potential antimicrobial and anticancer agents",

abstract = "Several novel benzoxaborole derivatives were synthesized starting from 2-formylphenylboronic acid utilizing Baylis-Hillman reaction, Barbier allylation, Passerini reaction, and aldol reaction protocols as the key step. All the synthesized benzoxaboroles have been evaluated for their antibacterial, antifungal, and anticancer activities.",

author = "\{Sravan Kumar\}, J. and Alam, \{M. A.\} and Shirisha Gurrapu and Grady Nelson and Michael Williams and Corsello, \{Michael A.\} and Johnson, \{Joseph L.\} and Jonnalagadda, \{Subash C.\} and Mereddy, \{Venkatram R.\}",

year = "2013",

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volume = "50",

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T1 - Synthesis and biological evaluation of novel benzoxaboroles as potential antimicrobial and anticancer agents

AU - Sravan Kumar, J.

AU - Alam, M. A.

AU - Gurrapu, Shirisha

AU - Nelson, Grady

AU - Williams, Michael

AU - Corsello, Michael A.

AU - Johnson, Joseph L.

AU - Jonnalagadda, Subash C.

AU - Mereddy, Venkatram R.

PY - 2013/7

Y1 - 2013/7

N2 - Several novel benzoxaborole derivatives were synthesized starting from 2-formylphenylboronic acid utilizing Baylis-Hillman reaction, Barbier allylation, Passerini reaction, and aldol reaction protocols as the key step. All the synthesized benzoxaboroles have been evaluated for their antibacterial, antifungal, and anticancer activities.

AB - Several novel benzoxaborole derivatives were synthesized starting from 2-formylphenylboronic acid utilizing Baylis-Hillman reaction, Barbier allylation, Passerini reaction, and aldol reaction protocols as the key step. All the synthesized benzoxaboroles have been evaluated for their antibacterial, antifungal, and anticancer activities.

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DO - 10.1002/jhet.1777

M3 - Article

AN - SCOPUS:84880931354

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SP - 814

EP - 820

JO - Journal of Heterocyclic Chemistry

JF - Journal of Heterocyclic Chemistry

IS - 4

ER -

Synthesis and biological evaluation of novel benzoxaboroles as potential antimicrobial and anticancer agents

Abstract

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