Synthesis and biological evaluation of novel benzoxaboroles as potential antimicrobial and anticancer agents

J. Sravan Kumar, M. A. Alam, Shirisha Gurrapu, Grady Nelson, Michael Williams, Michael A. Corsello, Joseph L. Johnson, Subash C. Jonnalagadda, Venkatram R. Mereddy

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Several novel benzoxaborole derivatives were synthesized starting from 2-formylphenylboronic acid utilizing Baylis-Hillman reaction, Barbier allylation, Passerini reaction, and aldol reaction protocols as the key step. All the synthesized benzoxaboroles have been evaluated for their antibacterial, antifungal, and anticancer activities.

Original languageEnglish (US)
Pages (from-to)814-820
Number of pages7
JournalJournal of Heterocyclic Chemistry
Volume50
Issue number4
DOIs
StatePublished - Jul 1 2013

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