Abstract
Three prostaglandin endoperoxide analogs that possess the 2,3‐diazabicyclo[2.2.1]heptane skeleton were synthesized and evaluated for activity in human platelets and in the rat fundus. All three compounds were inactive in inhibiting or stimulating platelet aggregation. One compound possessed weak contracting activity on the rat fundus.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1007-1010 |
| Number of pages | 4 |
| Journal | Journal of Pharmaceutical Sciences |
| Volume | 69 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 1980 |
Keywords
- Platelet aggregation—evaluation of inhibition and stimulation by prostaglandin endoperoxide analogs
- Prostaglandin endoperoxide analogs—synthesis and evaluation for inhibition and stimulation of platelet aggregation