Synthesis and antiviral evaluation of 4′-(1,2,3-triazol-1-yl) thymidines

Keyphrases

• Synthetic Evaluation 100%
• Azido Group 100%
• Thymidine 100%
• Antiviral Screening 100%
• 1,2,3-triazol 100%
• Human Immunodeficiency Virus Type 1 (HIV-1) 66%
• Inhibition Rate 66%
• Hepatitis C Virus 66%
• 1,2,3-triazole 66%
• Azidothymidine 66%
• West Nile Virus 33%
• Influenza Virus 33%
• AIDS/HIV 33%
• Medicinal Chemistry 33%
• Novel Antivirals 33%
• Obligate 33%
• Potent Inhibitor 33%
• Azide-alkyne Cycloaddition 33%
• Nucleosides 33%
• Cu-catalyzed 33%
• Antiviral nucleoside 33%
• Antiviral Potency 33%
• Triazole Analogues 33%
• Ethynyl Group 33%
• Nucleoside Scaffold 33%
• Antiviral Drug Discovery 33%
• Target Binding 33%
• Chemical Manipulation 33%
• Steric Barriers 33%

Chemistry

• % Inhibition 100%
• Nucleoside 100%
• Azido Group 100%
• 1,2,3-triazole 100%
• Thymidine 100%
• Zidovudine 100%
• Chemistry 50%
• Azide 50%
• Ethynyl 50%
• Alkyne 50%
• Cycloaddition 50%
• Triazole 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Antivirus Agent 100%
• Thymidine 100%
• Hepatitis C Virus 40%
• Zidovudine 40%
• Human Immunodeficiency Virus 1 40%
• Triazole Derivative 40%
• Nucleoside 40%
• HIV 20%
• Pharmaceutical Chemistry 20%
• Azide 20%
• Alkyne 20%
• West Nile Virus 20%
• Triazole 20%
• Influenza A Virus 20%