Syntheses of novel C-9 and C-10 modified bioactive taxanes

Apurba Datta; David G. Vander Velde; Gunda I. Georg; Richard H. Himes

doi:10.1016/0040-4039(95)00208-T

Syntheses of novel C-9 and C-10 modified bioactive taxanes

Apurba Datta, David G. Vander Velde, Gunda I. Georg, Richard H. Himes

Medicinal Chemistry

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A method has been developed for the syntheses of hitherto unreported C-9 and C-10 modified taxanes. These analogs demonstrated excellent to good cytotoxicity against B 16 melanoma cells.

Original language	English (US)
Pages (from-to)	1985-1988
Number of pages	4
Journal	Tetrahedron Letters
Volume	36
Issue number	12
DOIs	https://doi.org/10.1016/0040-4039(95)00208-T
State	Published - Mar 20 1995

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@article{504a4a0d0bb84749b3639481e35750fd,

title = "Syntheses of novel C-9 and C-10 modified bioactive taxanes",

abstract = "A method has been developed for the syntheses of hitherto unreported C-9 and C-10 modified taxanes. These analogs demonstrated excellent to good cytotoxicity against B 16 melanoma cells.",

author = "Apurba Datta and {Vander Velde}, {David G.} and Georg, {Gunda I.} and Himes, {Richard H.}",

year = "1995",

month = mar,

day = "20",

doi = "10.1016/0040-4039(95)00208-T",

language = "English (US)",

volume = "36",

pages = "1985--1988",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "12",

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TY - JOUR

T1 - Syntheses of novel C-9 and C-10 modified bioactive taxanes

AU - Datta, Apurba

AU - Vander Velde, David G.

AU - Georg, Gunda I.

AU - Himes, Richard H.

PY - 1995/3/20

Y1 - 1995/3/20

N2 - A method has been developed for the syntheses of hitherto unreported C-9 and C-10 modified taxanes. These analogs demonstrated excellent to good cytotoxicity against B 16 melanoma cells.

AB - A method has been developed for the syntheses of hitherto unreported C-9 and C-10 modified taxanes. These analogs demonstrated excellent to good cytotoxicity against B 16 melanoma cells.

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UR - http://www.scopus.com/inward/citedby.url?scp=0028945181&partnerID=8YFLogxK

U2 - 10.1016/0040-4039(95)00208-T

DO - 10.1016/0040-4039(95)00208-T

M3 - Article

AN - SCOPUS:0028945181

SN - 0040-4039

VL - 36

SP - 1985

EP - 1988

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 12

ER -

Syntheses of novel C-9 and C-10 modified bioactive taxanes

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