Syncope: Causes, clinical evaluation, and current therapy

David G Benditt, Stephen Remole, Simon Milstein, Steven Bailin

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


Syncope is a common clinical problem comprising the sudden loss of both consciousness and postural tone, with a subsequent spontaneous and relatively prompt recovery. Often it is difficult to differentiate a true syncopal spell from other conditions, such as seizure disorders, or from some simple accidents. Even more difficult is the identification of the cause of syncopal episodes. Nonetheless, establishing a definitive diagnosis is an important task given the high risk of recurrent symptoms. Careful use of noninvasive and invasive cardiovascular studies (including electrophysiologic testing and tilt-table testing) along with selected hematologic, biochemical, and neurologic studies provides, in the majority of cases, the most effective strategy for obtaining a specific diagnosis and for directing therapy.

Original languageEnglish (US)
Pages (from-to)283-300
Number of pages18
JournalAnnual review of medicine
Issue number1
StatePublished - 1992


  • Electrophysiologic studies
  • Fainting
  • Tilt-table testing


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