Syncope and the autonomic nervous system

Keith Lurie, David Benditt

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


The autonomic nervous system plays a central role in the maintenance of hemodynamic stability. Dysfunction of this complex regulatory system can lead to the development of loss of consciousness. This article summarizes our current understanding of the role of the autonomic nervous system in maintaining a stable blood pressure and heart rate under normal and abnormal physiologic conditions. The role of baroreceptors, mechanoreceptors, chemoreceptors, vascular reactivity, and the interaction of these sensor systems with the central nervous system as a whole are reviewed. Current concepts related to the mechanisms of unexplained syncope and the 'state-of- the-art' diagnostic and treatment options are also discussed.

Original languageEnglish (US)
Pages (from-to)760-776
Number of pages17
JournalJournal of cardiovascular electrophysiology
Issue number8
StatePublished - 1996


  • baroreceptors
  • central nervous system
  • heart
  • mechanoreceptors
  • tilt table testing
  • vasovagal syncope


Dive into the research topics of 'Syncope and the autonomic nervous system'. Together they form a unique fingerprint.

Cite this