Swelling Gliotransmission by SWELL1 Channels

Research output: Contribution to journalShort survey

Abstract

Astrocytes release glutamate, which can modulate nearby synapses, but how this release is accomplished remains debated. In this issue of Neuron, Yang et al. (2019) show that the volume-regulated anion channel Swell1 in astrocytes mediates the release of glutamate and impacts synaptic transmission, learning and memory, and neurotoxicity. Astrocytes release glutamate, which can modulate nearby synapses, but how this release is accomplished remains debated. In this issue of Neuron, Yang et al. (2019) show that the volume-regulated anion channel Swell1 in astrocytes mediates the release of glutamate and impacts synaptic transmission, learning and memory, and neurotoxicity.

Original languageEnglish (US)
Pages (from-to)711-713
Number of pages3
JournalNeuron
Volume102
Issue number4
DOIs
StatePublished - May 22 2019

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