Sweet syndrome with pseudocarcinomatous hyperplasia: A case report and review of the literature

Angela Wipf, Heidi Wipf, Daniel D Miller

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Pseudocarcinomatous (pseudoepitheliomatous) hyperplasia represents reactive epidermal change mimicking squamous cell carcinoma (SCC), owing to a variety of inflammatory and neoplastic phenomena, including deep fungal infections, CD30-positive lymphomas, and others. We report a case of Sweet syndrome (SS) arising in a patient with acute myelogenous leukemia, with persistent orolabial involvement which mimicked SCC both clinically and microscopically, but resolved entirely with adequate corticosteroid treatment. Clinicians should be aware that neutrophilic dermatoses such as SS and pyoderma gangrenosum may rarely exhibit pseudocarcinomatous epidermal changes similar to those seen in soft tissue infections and other inflammatory dermatoses.

Original languageEnglish (US)
Pages (from-to)520-527
Number of pages8
JournalJournal of cutaneous pathology
Volume46
Issue number7
DOIs
StatePublished - Jul 2019

Keywords

  • Sweet syndrome
  • pseudocarcinomatous hyperplasia
  • pseudoepitheliomatous hyperplasia

PubMed: MeSH publication types

  • Case Reports
  • Journal Article
  • Review

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