Abstract
Maternal nutrition and metabolic health status during pregnancy are critical factors that shape the life-long health trajectory of offspring. Altered nutrition during specific times of development in utero can lead to functional changes in tissues such as the pancreatic β-cells, predisposing those tissues to metabolic diseases and Type 2 diabetes that manifest later in life. This chapter will focus on the role of pregnancy complications with altered nutrition during gestation in the maladaptive programming of β-cell mass and function in the offspring.
| Original language | English (US) |
|---|---|
| Title of host publication | Advances in Anatomy Embryology and Cell Biology |
| Publisher | Springer Science and Business Media Deutschland GmbH |
| Pages | 157-197 |
| Number of pages | 41 |
| State | Published - 2024 |
Publication series
| Name | Advances in Anatomy Embryology and Cell Biology |
|---|---|
| Volume | 239 |
| ISSN (Print) | 0301-5556 |
| ISSN (Electronic) | 2192-7065 |
Bibliographical note
Publisher Copyright:© The Author(s), under exclusive license to Springer Nature Switzerland AG 2024.
Keywords
- Diabetes
- DOHaD pancreas development
- Gestational diabetes
- Islets
- Low protein
- Maternal health
- Maternal obesity
PubMed: MeSH publication types
- Journal Article
- Review
