Sustained B7/CD28 interactions and resultant phosphatisylinositol 3-kinase activity maintain G₁→S phase transitions at an optimal rate

Keyphrases

• Phase Transition 100%
• CD28 100%
• Kinase Activity 100%
• Optimal Rate 100%
• Cell Division 66%
• CD4+ T Cells 66%
• Interleukin-2 66%
• High Concentration 66%
• T Cells 33%
• Growth Factors 33%
• Peptide-MHC Complex 33%
• Pharmacologic 33%
• CD28 Costimulation 33%
• Clonal Expansion 33%
• Signaling Cascades 33%
• Abrogation 33%
• Costimulatory Ligand 33%
• Cell Division Rate 33%
• Phosphatidylinositol 3-kinase/Akt Signaling 33%
• Expansion Responses 33%
• IL-2R Signaling 33%
• Costimulatory Molecules 33%

Neuroscience

• Kinase 100%
• CD28 100%
• Cell Division 75%
• T Cell 75%
• CD4 50%
• Interleukin 2 50%
• Cell Cycle 25%
• Phosphoinositide 3-Kinase 25%
• Akt Signaling 25%
• Major Histocompatibility Antigen 25%
• Growth Factor 25%

Immunology and Microbiology

• CD28 100%
• T Cell Receptor 75%
• Cell Division 75%
• T-Helper Cell 50%
• Interleukin 2 50%
• Growth Factor 25%
• Akt Signaling 25%
• Major Histocompatibility Antigen 25%
• T Cell 25%
• Cell Cycle 25%