Abstract
This report describes a case of refractory ionised hypercalcaemia, of 12 months duration, in an 11-year-old, male, neutered beagle diagnosed with metastatic histiocytic sarcoma at postmortem examination. In this case, the parathyroid hormone levels were at the lower end of the reference interval, the parathyroid hormone-related peptide was unmeasurable/Low, and 25-hydroxycholcalciferol was within reference range, while calcitriol levels were inappropriately high (although at the top of reference range), suggesting that the ionised hypercalcaemia was mediated via excessive calcitriol secretion.
| Original language | English (US) |
|---|---|
| Article number | e70104 |
| Journal | Veterinary Record Case Reports |
| Volume | 13 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 2025 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2025 The Author(s). Veterinary Record Case Reports published by John Wiley & Sons Ltd on behalf of British Veterinary Association.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- calcitriol
- ionised hypercalcaemia
- metastatic histiocytic sarcoma
- non-PTHrP
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