Susceptibilities of enterococci to twelve antibiotics

R. W. Tofte, J. A. Solliday, K. B. Crossley

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

The susceptibilities of 347 urine isolates of enterococci (Streptococcus faecalis, 44%; S. faecalis subsp. zymogenes, 37%; S. faecalis subsp. liquefaciens, 19%) to ampicillin, azlocillin, mezlocillin, piperacillin, vancomycin, gentamicin, erythromycin, rosaramicin, rifampin, rifampin plus trimethoprim (1:4), trimethoprim-sulfamethoxazole (1:20), and chloramphenicol were determined by the agar dilution technique. There were no significant differences in susceptibility to individual agents among the subspecies of S. faecalis. Azlocillin and mezlocillin (MIC for 90% of isolates, 0.78 μg/ml) and piperacillin, ampicillin and vancomycin (MIC for 90% of isolates, 1.56 μg/ml) were the most active agents and were significantly more potent than the other reference antibiotics tested.

Original languageEnglish (US)
Pages (from-to)532-533
Number of pages2
JournalAntimicrobial agents and chemotherapy
Volume25
Issue number4
DOIs
StatePublished - 1984

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