Abstract
Bordetella pertussis and other Bordetella species cause respiratory infections in humans and in a variety of animals. Clinical isolates of B. pertussis have multiple virulence factors, several of which have been reported to induce protective immunity. Using cell surface iodination techniques and monoclonal antibody immunoblots we have identified several proteins which are exposed on the surface of B. pertussis cells, including the filamentous hemagglutinin and outer membrane proteins 91, 18, and 15. Protein 91 is unique to virulent B. pertussis strains. Antibodies to protein 18 are found in convalescent serum of both humans and mice recovering from infection with B. pertussis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 117-127 |
| Number of pages | 11 |
| Journal | Advances in experimental medicine and biology |
| Volume | 185 |
| DOIs | |
| State | Published - 1985 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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