Surface antigens of Bordetella pertussis.

C. D. Parker, S. K. Armstrong, D. W. Frank

Research output: Contribution to journalArticlepeer-review


Bordetella pertussis and other Bordetella species cause respiratory infections in humans and in a variety of animals. Clinical isolates of B. pertussis have multiple virulence factors, several of which have been reported to induce protective immunity. Using cell surface iodination techniques and monoclonal antibody immunoblots we have identified several proteins which are exposed on the surface of B. pertussis cells, including the filamentous hemagglutinin and outer membrane proteins 91, 18, and 15. Protein 91 is unique to virulent B. pertussis strains. Antibodies to protein 18 are found in convalescent serum of both humans and mice recovering from infection with B. pertussis.

Original languageEnglish (US)
Pages (from-to)117-127
Number of pages11
JournalAdvances in experimental medicine and biology
StatePublished - 1985


Dive into the research topics of 'Surface antigens of Bordetella pertussis.'. Together they form a unique fingerprint.

Cite this