TY - JOUR
T1 - Surface antigens of Bordetella pertussis.
AU - Parker, C. D.
AU - Armstrong, S. K.
AU - Frank, D. W.
PY - 1985
Y1 - 1985
N2 - Bordetella pertussis and other Bordetella species cause respiratory infections in humans and in a variety of animals. Clinical isolates of B. pertussis have multiple virulence factors, several of which have been reported to induce protective immunity. Using cell surface iodination techniques and monoclonal antibody immunoblots we have identified several proteins which are exposed on the surface of B. pertussis cells, including the filamentous hemagglutinin and outer membrane proteins 91, 18, and 15. Protein 91 is unique to virulent B. pertussis strains. Antibodies to protein 18 are found in convalescent serum of both humans and mice recovering from infection with B. pertussis.
AB - Bordetella pertussis and other Bordetella species cause respiratory infections in humans and in a variety of animals. Clinical isolates of B. pertussis have multiple virulence factors, several of which have been reported to induce protective immunity. Using cell surface iodination techniques and monoclonal antibody immunoblots we have identified several proteins which are exposed on the surface of B. pertussis cells, including the filamentous hemagglutinin and outer membrane proteins 91, 18, and 15. Protein 91 is unique to virulent B. pertussis strains. Antibodies to protein 18 are found in convalescent serum of both humans and mice recovering from infection with B. pertussis.
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U2 - 10.1007/978-1-4684-7974-4_7
DO - 10.1007/978-1-4684-7974-4_7
M3 - Article
C2 - 2866677
AN - SCOPUS:0022317379
SN - 0065-2598
VL - 185
SP - 117
EP - 127
JO - Advances in experimental medicine and biology
JF - Advances in experimental medicine and biology
ER -
