Superficial neuroendocrine carcinoma of the esophagus

Takeshi Iwamura, Naoya Shibata, Paula Termuhlen, Motoaki Nagano, Hiromi Yamada, Kinta Hatakeyama, Toru Hayashi, Kiyokazu Toyoda

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


A 50-year-old man underwent subtotal esophagectomy for a superficial ulcerated tumor, 1.8 cm in length, located in the middle third of the esophagus. Histological examination of the resected specimen showed a stage I infiltrating neuroendocrine carcinoma. Tumor cells were immunohistochemically positive for chromogranin A, neuron-specific enolase, synaptophysin, protein gene product 9.5 and carcinoembryonic antigen. Postoperative cisplatin-based chemoradiation therapy was administered. Fourteen months after surgery, widely metastatic disease was noted and the patient died 3 months later.

Original languageEnglish (US)
Pages (from-to)216-219
Number of pages4
JournalDigestive Endoscopy
Issue number4
StatePublished - 2001


  • Esophagus
  • Neuroendocrine carcinoma
  • Small cell carcinoma


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