Superficial neuroendocrine carcinoma of the esophagus

Takeshi Iwamura, Naoya Shibata, Paula Termuhlen, Motoaki Nagano, Hiromi Yamada, Kinta Hatakeyama, Toru Hayashi, Kiyokazu Toyoda

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Abstract

A 50-year-old man underwent subtotal esophagectomy for a superficial ulcerated tumor, 1.8 cm in length, located in the middle third of the esophagus. Histological examination of the resected specimen showed a stage I infiltrating neuroendocrine carcinoma. Tumor cells were immunohistochemically positive for chromogranin A, neuron-specific enolase, synaptophysin, protein gene product 9.5 and carcinoembryonic antigen. Postoperative cisplatin-based chemoradiation therapy was administered. Fourteen months after surgery, widely metastatic disease was noted and the patient died 3 months later.

Original languageEnglish (US)
Pages (from-to)216-219
Number of pages4
JournalDigestive Endoscopy
Volume13
Issue number4
DOIs
StatePublished - Dec 1 2001

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Keywords

  • Esophagus
  • Neuroendocrine carcinoma
  • Small cell carcinoma

Cite this

Iwamura, T., Shibata, N., Termuhlen, P., Nagano, M., Yamada, H., Hatakeyama, K., Hayashi, T., & Toyoda, K. (2001). Superficial neuroendocrine carcinoma of the esophagus. Digestive Endoscopy, 13(4), 216-219. https://doi.org/10.1046/j.1443-1661.2001.00146.x