Super-resolution imaging for monitoring cytoskeleton dynamics

Solaire A. Finkenstaedt-Quinn, Tian A. Qiu, Kayeong Shin, Christy L. Haynes

Research output: Contribution to journalReview article

8 Scopus citations


The cytoskeleton is a key cellular structure that is important in the control of cellular movement, structure, and sensing. To successfully image the individual cytoskeleton components, high resolution and super-resolution fluorescence imaging methods are needed. This review covers the three basic cytoskeletal elements and the relative benefits and drawbacks of fixed versus live cell imaging before moving on to recent studies using high resolution and super-resolution techniques. The techniques covered include the near-diffraction limited imaging methods of confocal microscopy and TIRF microscopy and the super-resolution fluorescence imaging methods of STORM, PALM, and STED.

Original languageEnglish (US)
Pages (from-to)5674-5688
Number of pages15
Issue number20
StatePublished - Oct 21 2016

Fingerprint Dive into the research topics of 'Super-resolution imaging for monitoring cytoskeleton dynamics'. Together they form a unique fingerprint.

  • Cite this

    Finkenstaedt-Quinn, S. A., Qiu, T. A., Shin, K., & Haynes, C. L. (2016). Super-resolution imaging for monitoring cytoskeleton dynamics. Analyst, 141(20), 5674-5688.