Le sulfatide: un glycolipide plurifonctionnel constituant des membranes biologiques.

Translated title of the contribution: Sulfatide: a multifunctional glycolipid constituent of biological membranes

B. Zalc, F. B. Craves, M. Monge, L. Leybin, H. Loh, N. Baumann

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Sulfogalactosylceramide (or sulfatide) has been localized in the central nervous system by indirect immunofluorescence. This glycosphingolipid belongs essentially to the myelinated areas. Nevertheless, it has also been found in ependymal cells, subpial processes and, in the cerebellum, in the Bergmann fibers. In the brain areas, known to be enriched in opiate receptors, some cells and nerve terminals are also sulfatide positive. In this latter localization, opiates were shown to selectively inhibit binding of the antisulfatide antibodies. We have also shown that antisulfatide inhibited, in vitro, the stereo-specific binding of narcotic drugs and that they antagonized the in vivo effects of morphine and beta-endorphin.

Translated title of the contributionSulfatide: a multifunctional glycolipid constituent of biological membranes
Original languageFrench
Pages (from-to)457-466
Number of pages10
JournalComptes Rendus des Seances de la Societe de Biologie et de Ses Filiales
Volume174
Issue number4
StatePublished - Dec 1 1980

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