Successful use of propofol in refractory delirium tremens

T. R. Coomes, S. W. Smith

Research output: Contribution to journalArticlepeer-review

78 Scopus citations


Alcohol withdrawal is a common problem encountered by emergency physicians, with delirium tremens (DT) as the extreme manifestation. DT is a true medical emergency. Although benzodiazepines are the mainstay of therapy, some patients require massive amounts to control their symptoms. We report the successful use of propofol for DT refractory to benzodiazepines in a 42- year-old alcoholic man. We briefly discuss alcohol withdrawal, as well as the pharmacokinetics and adverse affects of propofol. The use of propofol in treating DT refractory to benzodiazepines has previously not been reported.

Original languageEnglish (US)
Pages (from-to)825-828
Number of pages4
JournalAnnals of Emergency Medicine
Issue number6
StatePublished - 1997
Externally publishedYes


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