Capillary malformation-arteriovenous malformation (CM-AVM) syndrome is an autosomal dominant condition characterized by multifocal, noncontiguous pink patches on the skin that often have a surrounding pale halo. In some cases, an association with a fast flow, arteriovenous malformation (AVM) can be identified. Here, we describe a case report of a 16-year-old woman with CM-AVM syndrome and significant cardiac compromise successfully treated with trametinib, a mitogen-activated protein kinase (MEK) inhibitor.
Bibliographical noteFunding Information:
The authors thank Timothy Moss, MD PhD and Denise Adams, MD for their aid in the management decisions in this case.
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- MEK inhibitor
- skin signs of systemic disease
- vascular malformation
PubMed: MeSH publication types
- Case Reports
- Journal Article