Subclinical Proliferative Enteropathy in Sentinel Rabbits Associated with Lawsonia intracellularis

G. E. Duhamel, E. C. Klein, R. O. Elder, C. J. Gebhart

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Light microscopic and ultrastructural changes of naturally acquired proliferative enteropathy were observed in two of three young sentinel New Zealand White rabbits. The etiologic agent, Lawsonia intracellularis, was demonstrated in the tissues using morphologic, immunohistochemical, and molecular methods. Proliferative enteropathy was associated with infection of villous and crypt enterocytes by intracellular organisms genotypically and antigenically related to L. intracellularis of various other animal species.

Original languageEnglish (US)
Pages (from-to)300-303
Number of pages4
JournalVeterinary pathology
Issue number4
StatePublished - Jul 1998


  • Immunohistochemistry
  • Lawsonia intracellularis
  • Polymerase chain reaction
  • Proliferative enteropathy
  • Proliferative ileitis
  • Rabbits


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