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Subarachnoid hemorrhage associated with cyclosporine A neurotoxicity in a bone-marrow transplant recipient

  • M. Teksam
  • , S. O. Casey
  • , E. Michel
  • , C. L. Truwit

Research output: Contribution to journalArticlepeer-review

Abstract

We report subarachnoid hemorrhage associated with cyclosporine A (CSA) neurotoxicity after bone-marrow transplantation for chronic myelogenous leukemia. CT showed occipital subarachnoid hemorrhage. MRI confirmed this, and demonstrated cortical and subcortical edema in the posterior temporal, occipital, and posterior frontal lobes bilaterally, which was typical of CSA neurotoxicity. Recognition of CSA neurotoxicity as the cause of the subarachnoid hemorrhage obviated angiographic investigation. After cessation of cyclosporine therapy, the cortical and subcortical edema resolved on follow-up MRI with some residual blood products in the subarachnoid space.

Original languageEnglish (US)
Pages (from-to)242-245
Number of pages4
JournalNeuroradiology
Volume43
Issue number3
DOIs
StatePublished - 2001

Bibliographical note

Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Bone marrow transplantation
  • Cyclosporine A
  • Hemorrhage, subarachnoid

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