Study of the hydrogen bond donor acidity of binary aqueous mixtures and their role in reversed‐phase liquid chromatography

Jung Hag Park, Andrew J. Dallas, Phoebe Chau, Peter W. Carr

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

The solvatochromic hydrogen bond donor (HBD) acidity parameter (αmix) of aqueous mixtures of methanol, acetonitrile, propan‐2‐ol and tetrahydrofuran were determined spectrophotometrically. The study was carried out at 25deg;C as a function of composition. The indicators used were 2,6‐diphenyl‐4‐(2,4,6‐triphenyl‐N‐pyridino)phenolate, 2,6‐dichloro‐4‐(2,4,6‐triphenyl‐N‐pyridino)phenolate and Fe(LL)2(CN)2 (LL = N‐(2‐pyridylbenzylidene)‐3,4‐dimethylaniline). The HBD acidity of the aqueous organic mixtures was related to retention in reversed‐phase liquid chromatography.

Original languageEnglish (US)
Pages (from-to)757-769
Number of pages13
JournalJournal of Physical Organic Chemistry
Volume7
Issue number12
DOIs
StatePublished - Dec 1994

Fingerprint

Dive into the research topics of 'Study of the hydrogen bond donor acidity of binary aqueous mixtures and their role in reversed‐phase liquid chromatography'. Together they form a unique fingerprint.

Cite this