Studies towards the synthesis of methionine aminopeptidase inhibitors: Diversification utilizing a ROMP-derived coupling reagent

Keyphrases

• Metathesis Polymerization 100%
• Coupling Agent 100%
• Methionine Aminopeptidase Inhibitors 100%
• Microwave-assisted 50%
• High Mass Loading 50%
• In Silico 50%
• X-ray Crystallography 50%
• Structural Features 50%
• Suzuki Coupling 50%
• Docking Studies 50%
• Biological Testing 50%
• Compound Library 50%
• SAR Study 50%
• Chromatographic Purification 50%
• Methionine Aminopeptidase (MetAP) 50%
• ADME Properties 50%
• Heterocyclic Amides 50%
• Chromatography-free Synthesis 50%
• Arylboronic Acids 50%

Chemistry

• Polymerization 100%
• Methionine 100%
• Carboxamide 33%
• Heterocyclic Compound 33%
• X-Ray Crystallography 33%
• Suzuki Reaction 33%