Structure/property relationships for two-photon absorbing fluorophores

M. Rumi, J. Ehrlich, A. Heikal, J. Fu, S. Barlow, M. D. Levin, L. Erskine, M. Lipson, D. McCord-Maughon, H. Rockel, G. Subramaniam, S. Thayumanavan, S. R. Marder, J. W. Perry, M. Albota, al et al

Research output: Contribution to conferencePaperpeer-review


The position and strength of the band of the two-photon absorption peak in conjugated molecules can be controlled by varying the conjugation length and also by appropriate substitution of the molecule with electron donating and electron withdrawing groups. In this study, several new agents have been developed that have strong two-photon absorptivities and two-photon absorption wavelengths that are ideally suited for imaging of tissue using a Ti:sapphire laser operating between 700 and 950 nm. Preliminary evidence suggest that inclusion of heavy atoms leads to efficient formation of triplets and formation of singlet oxygen.

Original languageEnglish (US)
Number of pages1
StatePublished - 1998
EventProceedings of the 1998 Conference on Lasers and Electro-Optics, CLEO - San Francisco, CA, USA
Duration: May 3 1998May 8 1998


OtherProceedings of the 1998 Conference on Lasers and Electro-Optics, CLEO
CitySan Francisco, CA, USA


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