Structure of the ATP-synthase studied by electron microscopy and image processing

Vladimir L. Tsuprun; Elena V. Orlova; Irina V. Mesyanzhinova

doi:10.1016/0014-5793(89)80545-9

Structure of the ATP-synthase studied by electron microscopy and image processing

Vladimir L. Tsuprun, Elena V. Orlova, Irina V. Mesyanzhinova

Otolaryngology

Research output: Contribution to journal › Article › peer-review

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Abstract

The structure of ATP synthase from beef heart mitochondria has been studied by electron microscopy and image processing using negatively stained specimens of detergent-solubilized and membrane-bound molecules. The F₁-ATPase and the membrane-embedded F₀ sector of ATP synthase are found to be connected by a narrow stalk, 4-4.5 nm long and 3-3.5 nm wide, projecting about 4.2 nm from the membrane surface. The F₀ sector has a globular shape, 6-8 nm in diameter and, in part, extends from the membrane lipid bilayer.

Original language	English (US)
Pages (from-to)	279-282
Number of pages	4
Journal	FEBS Letters
Volume	244
Issue number	2
DOIs	https://doi.org/10.1016/0014-5793(89)80545-9
State	Published - Feb 27 1989

Keywords

ATP synthase
Electron microscopy
Enzyme structure

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10.1016/0014-5793(89)80545-9

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title = "Structure of the ATP-synthase studied by electron microscopy and image processing",

abstract = "The structure of ATP synthase from beef heart mitochondria has been studied by electron microscopy and image processing using negatively stained specimens of detergent-solubilized and membrane-bound molecules. The F1-ATPase and the membrane-embedded F0 sector of ATP synthase are found to be connected by a narrow stalk, 4-4.5 nm long and 3-3.5 nm wide, projecting about 4.2 nm from the membrane surface. The F0 sector has a globular shape, 6-8 nm in diameter and, in part, extends from the membrane lipid bilayer.",

keywords = "ATP synthase, Electron microscopy, Enzyme structure",

author = "Tsuprun, {Vladimir L.} and Orlova, {Elena V.} and Mesyanzhinova, {Irina V.}",

year = "1989",

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AU - Tsuprun, Vladimir L.

AU - Orlova, Elena V.

AU - Mesyanzhinova, Irina V.

PY - 1989/2/27

Y1 - 1989/2/27

N2 - The structure of ATP synthase from beef heart mitochondria has been studied by electron microscopy and image processing using negatively stained specimens of detergent-solubilized and membrane-bound molecules. The F1-ATPase and the membrane-embedded F0 sector of ATP synthase are found to be connected by a narrow stalk, 4-4.5 nm long and 3-3.5 nm wide, projecting about 4.2 nm from the membrane surface. The F0 sector has a globular shape, 6-8 nm in diameter and, in part, extends from the membrane lipid bilayer.

AB - The structure of ATP synthase from beef heart mitochondria has been studied by electron microscopy and image processing using negatively stained specimens of detergent-solubilized and membrane-bound molecules. The F1-ATPase and the membrane-embedded F0 sector of ATP synthase are found to be connected by a narrow stalk, 4-4.5 nm long and 3-3.5 nm wide, projecting about 4.2 nm from the membrane surface. The F0 sector has a globular shape, 6-8 nm in diameter and, in part, extends from the membrane lipid bilayer.

KW - ATP synthase

KW - Electron microscopy

KW - Enzyme structure

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JO - FEBS Letters

JF - FEBS Letters

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ER -

Structure of the ATP-synthase studied by electron microscopy and image processing

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