TY - JOUR
T1 - Structure of de-oxy corticosterone (4-pregnen-21-ol-3, 20-dione)
AU - Dey, Raja
AU - Roychowdhury, Sandhya
AU - Roychowdhury, P.
AU - Righi, L.
PY - 1999/12
Y1 - 1999/12
N2 - Synthetic steroid de-oxy corticosterone (4-pregnen-21-ol-3,20-dione) crystallizes in the monoclinic space group P21, with a = 11.706(2); b = 11.171(3), c = 13.966(3) Å, and β = 100.94(2)°, Z = 4. Ring A tends to acquire the conformation of a half-boat, rings B and C are in the chair configuration, and ring D is a 13β, 14α-half-chair. The ring junctions B/C and C/D are both trans, whereas the ring junction A/B is quasi-trans. The molecule as a whole is slightly convex toward the β-side, with an angle of 16.01(0.36)° between the C10-C19 and C13 -C18 vectors. Molecular packing and stacking interactions play the major role in structural association. Cohesion of the crystal is due to van der Waals interactions.
AB - Synthetic steroid de-oxy corticosterone (4-pregnen-21-ol-3,20-dione) crystallizes in the monoclinic space group P21, with a = 11.706(2); b = 11.171(3), c = 13.966(3) Å, and β = 100.94(2)°, Z = 4. Ring A tends to acquire the conformation of a half-boat, rings B and C are in the chair configuration, and ring D is a 13β, 14α-half-chair. The ring junctions B/C and C/D are both trans, whereas the ring junction A/B is quasi-trans. The molecule as a whole is slightly convex toward the β-side, with an angle of 16.01(0.36)° between the C10-C19 and C13 -C18 vectors. Molecular packing and stacking interactions play the major role in structural association. Cohesion of the crystal is due to van der Waals interactions.
KW - 20-Dione
KW - 4-Pregnen-21-ol-3
KW - Crystal structure
KW - Pregnen
KW - Progestin
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U2 - 10.1023/A:1009556907495
DO - 10.1023/A:1009556907495
M3 - Article
AN - SCOPUS:0033233532
SN - 1074-1542
VL - 29
SP - 1271
EP - 1275
JO - Journal of Chemical Crystallography
JF - Journal of Chemical Crystallography
IS - 12
ER -