Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation

Keyphrases

• Methyltransferase 100%
• Polymerase Complex 100%
• Paramyxovirus 100%
• Viral 25%
• Animal Disease 25%
• Human Disease 25%
• Enzymatic Activity 25%
• RNA-dependent RNA Polymerase (RdRP) 25%
• Cryogenic Electron Microscopy 25%
• Phosphoprotein 25%
• X-ray Crystallography 25%
• High-resolution Structures 25%
• Active Sites 25%
• Structural Information 25%
• Polymerase 25%
• Viral Genome 25%
• Polymerase Domain 25%
• Oligomerization Domain 25%
• Entry Site 25%
• Large Proteins 25%
• Genome Replication 25%
• P Domain 25%
• Nucleoprotein N 25%
• π-complex 25%
• Exit Site 25%
• X-domain 25%
• Negative-sense RNA Virus 25%
• N-Serve 25%
• Methyltransferase Domain 25%
• 5′-end 25%
• Parainfluenza Virus 5 25%
• Mononegavirus 25%

Biochemistry, Genetics and Molecular Biology

• Conformation 100%
• Polymerase 100%
• C-Terminus 100%
• Paramyxoviridae 100%
• Methyltransferase 100%
• Active Site 25%
• RNA 25%
• X-Ray Crystallography 25%
• Transcription 25%
• Oligomerization 25%
• Protein L 25%
• Enzyme Activity 25%
• DNA Template 25%
• Virus Genome 25%
• Negative-Strand RNA Virus 25%
• Phosphoprotein 25%
• Nucleoprotein 25%
• RNA-dependent RNA Polymerase 25%
• Cryoelectron Microscopy 25%
• Parainfluenza Virus 5 25%