Structure-based design of HIV protease inhibitors: 5,6-dihydro-4- hydroxy-2-pyrones as effective, nonpeptidic inhibitors

Suvit Thaisrivongs, Donna L. Romero, Ruben A. Tommasi, Musiri N. Janakiraman, Joseph W. Strohbach, Steve R. Turner, Carolyn Biles, Raymond R. Morge, Paul D. Johnson, Paul A. Aristoff, Paul K. Tomich, Janet C. Lynn, Miao Miao Horng, Kong Teck Chong, Roger R. Hinshaw, W. Jeffrey Howe, Barry C. Finzel, Keith D. Watenpaugh