Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN

Keyphrases

• Exoribonuclease 100%
• Severe Acute Respiratory syndrome-CoV-2 100%
• Nsp10 50%
• Non-structural Protein 14 50%
• Active Sites 33%
• Computational Analysis 16%
• Innate Immunity 16%
• Molecular Dynamics Simulation 16%
• Coronavirus 16%
• Antiviral Drugs 16%
• Sofosbuvir 16%
• Mutational Analysis 16%
• CRISTAL 16%
• RNA-dependent RNA Polymerase (RdRP) 16%
• Multi-domain 16%
• Excise 16%
• Double-stranded RNA 16%
• Concave Surface 16%
• RNA Binding 16%
• RNA Primer 16%
• RNA Genome 16%
• RNA Substrates 16%
• RNA Recombination 16%
• Viral RNA-dependent RNA Polymerase 16%
• Basic Patch 16%
• Large RNAs 16%
• High-resolution Structure 16%
• Viral Virulence 16%
• Pregenomic RNA (pgRNA) 16%
• Exonuclease Activity 16%
• Nascent Strand 16%
• Exoribonuclease Activity 16%
• Terminal Amino Groups 16%

Biochemistry, Genetics and Molecular Biology

• Exoribonuclease 100%
• Active Site 28%
• RNA 28%
• RNA-dependent RNA Polymerase 28%
• Crystal Structure 14%
• N-Terminus 14%
• Double-Stranded RNA 14%
• Innate Immunity 14%
• DNA Template 14%
• RNA Binding 14%
• RNA Recombination 14%
• Virus Virulence 14%
• Exonuclease 14%
• Nucleotide 14%