Structure-Activity Relationship Studies on a Macrocyclic Agouti-Related Protein (AGRP) Scaffold Reveal Agouti Signaling Protein (ASP) Residue Substitutions Maintain Melanocortin-4 Receptor Antagonist Potency and Result in Inverse Agonist Pharmacology at the Melanocortin-5 Receptor

Mark D. Ericson, Katie T. Freeman, Sathya M. Schnell, Katlyn A. Fleming, Carrie Haskell-Luevano

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Pharmacology, Toxicology and Pharmaceutical Science