Structural heterogeneity of murine IgD during ontogeny

Roberta R. Pollock, Matthew F Mescher

Research output: Contribution to journalArticle

Abstract

We have studied the expression of the two membrane δ heavy chains (δ1 and δ2) and the two native IgD structures (IgD1 and IgDII) in neonatal mice. Both δ-chains appear simultaneously during development and neonatal mice, like adults, express equal amounts of δ1 and δ2 IgDI and IgDII also appear simultaneously during ontogeny and in the same ratio as expressed by adult mice of the same strain. Thus, when IgD first appears during ontogeny it shows the same structural heterogeneity as observed in adult mice.

Original languageEnglish (US)
Pages (from-to)1535-1540
Number of pages6
JournalMolecular Immunology
Volume19
Issue number12
DOIs
StatePublished - Jan 1 1982

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Immunoglobulin D
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Structural heterogeneity of murine IgD during ontogeny. / Pollock, Roberta R.; Mescher, Matthew F.

In: Molecular Immunology, Vol. 19, No. 12, 01.01.1982, p. 1535-1540.

Research output: Contribution to journalArticle

Pollock, Roberta R. ; Mescher, Matthew F. / Structural heterogeneity of murine IgD during ontogeny. In: Molecular Immunology. 1982 ; Vol. 19, No. 12. pp. 1535-1540.
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