Structural corroboration of two important building blocks of the anticancer drug eribulin mesylate through two-dimensional NMR and single-crystal X-ray diffraction studies

Keyphrases

• Anticancer Drugs 100%
• Two-dimensional NMR 100%
• Single Crystal X-ray Diffraction Study 100%
• Eribulin Mesylate 100%
• Methanol 33%
• Absolute Stereochemistry 33%
• Structural Integrity 33%
• NMR Data 33%
• Allyl 33%
• Absolute Configuration 33%
• Stereocenters 33%
• Structural Framework 33%
• X-ray Diffraction Data 33%
• Phenylsulfonyl 33%
• Eribulin 33%
• Monosolvate 33%
• Cyclohexylidene 33%
• Single Crystal X-ray Diffraction (SCXRD) 33%
• 2-methyltetrahydrofuran 33%

Chemistry

• Single Crystal X-Ray Diffraction 100%
• Two-Dimensional NMR 100%
• Eribulin Mesylate 100%
• Methanol 33%
• Stereochemistry 33%
• Tetrahydrofuran 33%
• NMR Data 33%
• Absolute Configuration 33%
• Eribulin 33%