Strongyloides hyperinfection following hematopoietic stem cell transplant in a patient with HTLV-1-associated T-cell leukemia

Jonathan D. Alpern, Sophie S. Arbefeville, Gregory Vercellotti, Patricia Ferrieri, Jaime S. Green

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Strongyloides stercoralis has the potential to cause accelerated autoinfection in immunocompromised hosts. Screening tests for strongyloidiasis may be falsely negative in the setting of immunosuppression. We report a case of Strongyloides hyperinfection syndrome in a patient with human T-lymphotropic virus type 1-associated T-cell leukemia early after hematopoietic stem cell transplant. The diagnosis was made by stool ova and parasite examination, despite a negative screening enzyme-linked immunosorbent assay. Because of anticipated prolonged neutropenia, an extended course of treatment was utilized.

Original languageEnglish (US)
Article numbere12638
JournalTransplant Infectious Disease
Volume19
Issue number1
DOIs
StatePublished - Feb 1 2017

Keywords

  • HTLV-1
  • Strongyloides hyperinfection syndrome
  • human T-lymphotropic virus type 1
  • strongyloidiasis

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