The joint U.S. and German Stratospheric Observatory for Infrared Astronomy (SOFIA), a program to develop and operate a 2.5-meter infrared airborne telescope in a Boeing 747SP, has obtained first science with the FORCAST camera in the 5 to 40 micron spectral region and the GREAT heterodyne spectrometer in the 130 to 240 micron spectral region. We briefly review the characteristics and status of the observatory. Spectacular science results on regions of star formation will be discussed. The FORCAST images show several discoveries and the potential for determining how massive stars form in our Galaxy. The GREAT heterodyne spectrometer has made mapping observations of the [C II] line at 158 microns, high J CO lines, and other molecular lines including SH. The HIPO high speed photometer and the high speed camera FDC were used to observe the 2011 June 23 UT stellar occultation by Pluto.