Strategies for the use of mixture-based synthetic combinatorial libraries: Scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods

Richard A. Houghten; Clemencia Pinilla; Marc A. Giulianotti; Jon R. Appela; Colette T. Dooley; Adel Nefzi; John M. Ostresh; Yongping Yu; Gerald M. Maggiora; Jose L. Medina-Franco; Daniela Brunner; Jeff Schneider

doi:10.1021/cc7001205

Strategies for the use of mixture-based synthetic combinatorial libraries: Scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods

Richard A. Houghten
, Clemencia Pinilla
, Marc A. Giulianotti
, Jon R. Appela
, Colette T. Dooley
, Adel Nefzi
, John M. Ostresh
, Yongping Yu
, Gerald M. Maggiora
, Jose L. Medina-Franco
, Daniela Brunner
, Jeff Schneider

Research output: Contribution to journal › Article › peer-review

Original language	English (US)
Pages (from-to)	3-19
Number of pages	17
Journal	Journal of Combinatorial Chemistry
Volume	10
Issue number	1
DOIs	https://doi.org/10.1021/cc7001205
State	Published - Jan 2008
Externally published	Yes

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10.1021/cc7001205

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Houghten, R. A., Pinilla, C., Giulianotti, M. A., Appela, J. R., Dooley, C. T., Nefzi, A., Ostresh, J. M., Yu, Y., Maggiora, G. M., Medina-Franco, J. L., Brunner, D., & Schneider, J. (2008). Strategies for the use of mixture-based synthetic combinatorial libraries: Scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods. Journal of Combinatorial Chemistry, 10(1), 3-19. https://doi.org/10.1021/cc7001205

Strategies for the use of mixture-based synthetic combinatorial libraries: Scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods. / Houghten, Richard A.; Pinilla, Clemencia ; Giulianotti, Marc A. et al.
In: Journal of Combinatorial Chemistry, Vol. 10, No. 1, 01.2008, p. 3-19.

Research output: Contribution to journal › Article › peer-review

Houghten, RA, Pinilla, C , Giulianotti, MA, Appela, JR, Dooley, CT, Nefzi, A, Ostresh, JM, Yu, Y, Maggiora, GM, Medina-Franco, JL, Brunner, D & Schneider, J 2008, 'Strategies for the use of mixture-based synthetic combinatorial libraries: Scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods', Journal of Combinatorial Chemistry, vol. 10, no. 1, pp. 3-19. https://doi.org/10.1021/cc7001205

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author = "Houghten, \{Richard A.\} and Clemencia Pinilla and Giulianotti, \{Marc A.\} and Appela, \{Jon R.\} and Dooley, \{Colette T.\} and Adel Nefzi and Ostresh, \{John M.\} and Yongping Yu and Maggiora, \{Gerald M.\} and Medina-Franco, \{Jose L.\} and Daniela Brunner and Jeff Schneider",

year = "2008",

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AU - Dooley, Colette T.

AU - Nefzi, Adel

AU - Ostresh, John M.

AU - Yu, Yongping

AU - Maggiora, Gerald M.

AU - Medina-Franco, Jose L.

AU - Brunner, Daniela

AU - Schneider, Jeff

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Strategies for the use of mixture-based synthetic combinatorial libraries: Scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods

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